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Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH4-induced reductive cyclization of 2-(4-chloro-2-cyano-2-phenylbutyl) aziridines and evaluation of their antimalarial activity

机译：通过LialH4诱导的2-（4-氯-2-氰基-2-苯基丁基）氮丙啶的还原环化合成2-氨基甲基-4-苯基-1-氮杂双环[2.2.1]庚烷并评价其抗疟活性

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D'hooghe, Matthias; Vervisch, Karel; Törnroos, Karl W; Verhaeghe, Tom; Desmet, Tom; Lategan, Carmen; Smith, Peter J; Chibale, Kelly; De Kimpe, Norbert;
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1. Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH4-induced reductive cyclization of 2-(4-chloro-2-cyano-2- phenylbutyl)aziridines and evaluation of their antimalarial activity [J] . DHoogheM., VervischK., T?rnroosK.W., Bioorganic and Medicinal Chemistry Letters . 2013,第5期

机译：通过LiAlH4诱导2-（4-氯-2-氰基-2-苯基丁基）偶氮化的二氨基甲基-4-苯基-1-邻苯基-1-氮杂环庚烷的合成α-（4-氯-2-氰基-2-苯基丁基）的抗疟疾活性
2. Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH4-induced reductive cyclization of 2-(4-chloro-2-cyano-2- phenylbutyl)aziridines and evaluation of their antimalarial activity [J] . DHoogheM., VervischK., T?rnroosK.W., Bioorganic and Medicinal Chemistry Letters . 2013,第5期

机译：通过LiAlH4诱导2-（4-氯-2-氰基-2-苯基丁基）偶氮化的二氨基甲基-4-苯基-1-邻苯基-1-氮杂环庚烷的合成α-（4-氯-2-氰基-2-苯基丁基）的抗疟疾活性
3. Spiroheterocyclic systems containing bridgehead nitrogen atom:synthesis,stereochemistry and antimicrobial activity of spiro(1'r)bicyclo [2.2.1] heptane-2',3-(4H)-[2H|-thiazolo [3,2-b]-s-tetrazines] and spiro [(1'r)-bicyclo [2.2.1] heptane-2',3-(4H)-[ [J] . Jag Mohan, Diksha Khatter Indian Journal of Heterocyclic Chemistry. (Text in English) . 2004,第4期

机译：含桥头氮原子的螺杂环体系：螺（1'r）双环[2.2.1]庚烷-2'，3-（4H）-[2H |-噻唑洛[3,2-b]-的合成，立体化学和抗菌活性s-tetrazines]和螺[[1'r）-双环[2.2.1]庚烷2'，3-（4H）-[
4. SYNTHESIS, REACTIVITY AND SELECTIVITY STUDIES ON CARBAGLYCAL-DERTVED W-PROTECTED AZIRIDINES 3α AND 3β AS NEW USEFUL CARBASUGARS SYNTHETIC TOOLS [C] . Valeria Di Bussolo, Ileana Frau, Paolo Crotti International Carbohydrate Symposium . 2013

机译：尸体型型碳粘纸的合成，反应性和选择性研究氮杂萘啶3α和3β作为新的有用的Carbasugars合成工具
5. SYNTHESIS AND SOLUTION PHASE SECONDARY ION MASS SPECTRAL STUDIES OF ANTINEOPLASTIC 1,4-BIS(2'-CHLOROETHYL)-1,4- DIAZABICYCLO(2.2.1)HEPTANE SALTS. [D] . GIESCHEN, DONALD PAUL. 1984

机译：抗肿瘤塑料1,4-双（2'-氯乙基）-1,4-二氮杂双环（2.2.1）庚烷盐的合成和溶液相二次离子质谱研究。
6. Multicomponent synthesis of some new (1S4S)-25-diazabicyclo2.2.1heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis [O] . Sujay Laskar, Luis Sánchez-Sánchez, Manuel López-Ortiz, 2017

机译：一些新的（1S4S）-25-二氮杂双环2.2.1庚烷-二硫代氨基甲酸酯的多组分合成及其对CaSkiMDA-MB-231和SK-Lu-1肿瘤细胞凋亡的体外抗增殖活性无坏死的诱导剂
7. LiAlH4-Induced Thia-Aza-Payne Rearrangement of Functionalized 2-(Thiocyanatomethyl)aziridines into 2-(Aminomethyl)thiiranes as an Entry to 5-(Chloromethyl)thiazolidin-2-ones [O] . Dolfen, Jeroen, Van Hecke, Kristof, D'hooghe, Matthias 2017

机译：LialH4诱导的官能化2-（硫氰酸根合甲基）氮丙啶的Thia-aza-payne重排成2-（氨基甲基）硫杂环戊烷作为5-（氯甲基）噻唑烷-2-酮的进入
8. Tandem Reduction/Cyclization of O-Nitrophenyl Propargyl Alcohols-A Novel Synthesis of 2- & 2,4-Disubstituted Quinolines and Application to the Synthesis of Streptonigrin; Doctoral thesis [R] . Sandelier, M. J. 2008

机译：O-硝基苯基炔丙醇的串联还原/环化 - 新型2-和2,4-二取代喹啉的合成及其在链霉素合成中的应用;博士论文

Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH4-induced reductive cyclization of 2-(4-chloro-2-cyano-2-phenylbutyl) aziridines and evaluation of their antimalarial activity

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